Sophia Jantzi's MSc Defence
Date and Time
Location
Room 141 and Teams: https://teams.microsoft.com/l/meetup-join/19%3ameeting_ZjRkYzgzMWEtNWRjZi00NDI3LWIxMzktMDQ1MTYzMmRkOTAz%40thread.v2/0?context=%7b%22Tid%22%3a%22be62a12b-2cad-49a1-a5fa-85f4f3156a7d%22%2c%22Oid%22%3a%22fbd28915-dda5-478f-8ecb-a3682dcf0c3a%22%7d
Details
Title: THE EFFECTS OF SACCHAROMYCES CEREVISIAE VAR. BOULARDII CNCM I-1079 SUPPLEMENTATION ON GUT BARRIER FUNCTION AND SYSTEMIC INFLAMMATION IN TRANSITION DAIRY COWS
Abstract:
The objectives of this thesis were 1) to determine the effects of Saccharomyces cerevisiae var. boulardii (SCB) CNCMI-1079 supplementation on gut permeability and systemic inflammation in transition dairy cows and 2) determine the effects of SCB supplementation on the inflammatory response following an acute systemic lipopolysaccharide (LPS) challenge. Overall, the first study found supplementing SCB tended to reduce gut permeability. The second study found the supplementation of SCB may have slightly reduced heart rate (HR) and respiratory rate (RR) and limited the increase in complete blood cell counts (CBC) following an intravenous (IV) LPS challenge. In summary, SCB supplementation may show promising benefits in decreasing gut permeability and reducing certain inflammatory response parameters following an endotoxin challenge however, further research is warranted.